South Dakota screens newborns through the Department of Health, with laboratory analysis by the State Hygienic Laboratory at the University of Iowa. The program reports no disorders “not screened,” indicating full RUSP coverage.
South Dakota newborn screening at a glance
- Conditions screened: about 55, plus newborn hearing and critical congenital heart disease (CCHD) screening
- Program: South Dakota Department of Health Newborn Screening
- Compared to the federal RUSP: screens the full RUSP core plus secondary conditions
- Official source: South Dakota newborn screening program
What the South Dakota panel covers
The panel includes PKU and other metabolic disorders, endocrine and hemoglobin conditions such as sickle cell disease, cystic fibrosis, and spinal muscular atrophy (SMA), plus X-ALD and Pompe disease, alongside hearing and CCHD screening.
South Dakota added X-ALD in June 2024 and lists no unscreened RUSP disorders, though it states coverage descriptively rather than as a single number.
Why the South Dakota panel stops where it does
The size of South Dakota’s panel is not a limit of technology. Every condition on a state panel has to clear evidence review, secure ongoing funding, and be formally adopted, which is why recent additions took years of work. Many treatable, childhood-onset conditions that today’s sequencing can already detect simply have not moved through that public-health pipeline yet.
How Fore extends newborn screening
Fore Genomics offers an at-home genetic screen that uses a simple cheek swab to look at the genes tied to more than 1,000 clinically actionable, childhood-onset conditions — well beyond any state panel. Samples are sequenced in CLIA-certified and CAP-accredited labs, and results are delivered with support from board-certified genetic counselors. It does not replace the South Dakota state screen; it extends it, using technology available today rather than waiting for the public program to expand. Compare all 50 states, read what newborn screening tests for, or start screening.
Frequently asked questions
How many conditions does South Dakota screen for?
South Dakota screens for about 55 through its bloodspot panel and point-of-care checks. Counts are approximate and change as the state updates its panel, so confirm current details with the South Dakota program.
Is newborn screening required in South Dakota?
Newborn screening is standard for every baby born in South Dakota. Rules on declining vary, so check current guidance from the South Dakota newborn screening program.
How do I get my baby’s South Dakota results?
Results are sent to your baby’s healthcare provider. Ask your pediatrician, or contact the South Dakota newborn screening program for a copy.
Medically reviewed by Fore’s Clinical Team. This article is for general educational purposes and is not medical advice. State screening panels change; confirm current details with the South Dakota Department of Health Newborn Screening (as of 2026). Sources: South Dakota newborn screening program; HRSA Recommended Uniform Screening Panel.