Minnesota runs one of the most comprehensive programs in the country through the Department of Health, screening for all 38 core and all 26 secondary RUSP conditions plus additional disorders beyond the federal panel.
Minnesota newborn screening at a glance
- Conditions screened: more than 60, plus newborn hearing and critical congenital heart disease (CCHD) screening
- Program: Minnesota Department of Health Newborn Screening Program
- Compared to the federal RUSP: exceeds the full RUSP (all 38 core + all 26 secondary)
- Official source: Minnesota newborn screening program
What the Minnesota panel covers
The panel includes PKU and other metabolic disorders, endocrine and hemoglobin conditions such as sickle cell disease, cystic fibrosis, SCID, and spinal muscular atrophy (SMA), plus metachromatic leukodystrophy (MLD) and congenital CMV.
Minnesota added MLD screening in 2025 and screens for cCMV, both beyond the federal RUSP. Its conditions page was last updated in June 2026.
Why the Minnesota panel stops where it does
The size of Minnesota’s panel is not a limit of technology. Every condition on a state panel has to clear evidence review, secure ongoing funding, and be formally adopted, which is why recent additions took years of work. Many treatable, childhood-onset conditions that today’s sequencing can already detect simply have not moved through that public-health pipeline yet.
How Fore extends newborn screening
Fore Genomics offers an at-home genetic screen that uses a simple cheek swab to look at the genes tied to more than 1,000 clinically actionable, childhood-onset conditions — well beyond any state panel. Samples are sequenced in CLIA-certified and CAP-accredited labs, and results are delivered with support from board-certified genetic counselors. It does not replace the Minnesota state screen; it extends it, using technology available today rather than waiting for the public program to expand. Compare all 50 states, read what newborn screening tests for, or start screening.
Frequently asked questions
How many conditions does Minnesota screen for?
Minnesota screens for more than 60 through its bloodspot panel and point-of-care checks. Counts are approximate and change as the state updates its panel, so confirm current details with the Minnesota program.
Is newborn screening required in Minnesota?
Newborn screening is standard for every baby born in Minnesota. Rules on declining vary, so check current guidance from the Minnesota newborn screening program.
How do I get my baby’s Minnesota results?
Results are sent to your baby’s healthcare provider. Ask your pediatrician, or contact the Minnesota newborn screening program for a copy.
Medically reviewed by Fore’s Clinical Team. This article is for general educational purposes and is not medical advice. State screening panels change; confirm current details with the Minnesota Department of Health Newborn Screening Program (as of June 2026). Sources: Minnesota newborn screening program; HRSA Recommended Uniform Screening Panel.