Every baby in the U.S. receives standard newborn screening through the state. Some families also choose supplemental genomic screening. Here is how the two compare, and why they work best together.
Standard (state) newborn screening
- Biochemical tests on a heel-prick blood spot, plus hearing and heart checks
- A fixed panel, typically 30 to 80 conditions depending on your state
- Provided automatically, at no cost to families
- Focused on urgent, treatable conditions that need action in infancy
Supplemental genomic screening
- DNA sequencing from a simple at-home cheek swab
- More than 1,000 clinically actionable conditions, plus 100+ medication-response markers
- Processed in CLIA-certified and CAP-accredited labs, with board-certified genetic counselor support
- An add-on that extends coverage well beyond the public panel
They work together
Supplemental screening does not replace state screening, it broadens it. State screening covers the urgent essentials for free; genomic screening covers far more conditions that the public panel cannot reach, because the limit there is budget and process, not technology. See how Fore works, what we screen for, or start screening.
Frequently asked questions
Do I still need state screening if I do genomic screening?
Yes. State screening is automatic and covers urgent, time-sensitive conditions. Genomic screening is a complement that broadens coverage.
What does supplemental screening cost?
Fore’s screen is $495 and is HSA/FSA eligible. See the product page for current details.
Medically reviewed by Fore’s Clinical Team. This article is for general educational purposes and is not medical advice. Sources: HRSA Recommended Uniform Screening Panel.